abstract：PURPOSE:To evaluate and compare the findings and changes of the anterior chamber angle configuration with indentation ultrasound biomicroscopy (UBM) gonioscopy in relative pupillary block (RPB), peripheral anterior synechia (PAS), and plateau iris configuration (PIC). METHODS:This study included 73 eyes of 52 patients...

journal_title：Journal of glaucoma

authors： Matsunaga K,Ito K,Esaki K,Sugimoto K,Sano T,Miura K,Sasoh M,Uji Y

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:To identify and characterize 'reversal' of optic nerve cupping following intraocular pressure (IOP) lowering in scanning laser tomography (SLT) longitudinal image series. METHODS:Modification was made to a previously described analytical approach to longitudinally study putatively increased rim area following ...

journal_title：Journal of glaucoma

authors： Tan JC,Hitchings RA

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:The most common reason for long-term failure of glaucoma filtering surgery (GFS) is scarring of the external filtering "bleb" tissues. The identification of the factors that mediate this process, as well as the development and initial testing of new therapies to limit scarring is enhanced by the use of appropri...

journal_title：Journal of glaucoma

authors： Sherwood MB,Esson DW,Neelakantan A,Samuelson DA

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:To clarify the mechanism by which bunazosin hydrochloride (BZ), a selective alpha1-adrenoceptor antagonist, increases uveoscleral outflow. METHODS:The effects of BZ on matrix metalloproteinase (MMP) activities in cultured monkey ciliary muscle cells, and on phenylephrine hydrochloride-induced constriction in b...

journal_title：Journal of glaucoma

authors： Akaishi T,Takagi Y,Matsugi T,Ishida N,Hara H,Kashiwagi K

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To compare central corneal thickness between eyes with congenital glaucoma and normal controls and to correlate this parameter with corneal diameter and axial length. METHODS:Eyes of consecutive children with congenital glaucoma with previous glaucoma surgery and eyes of children with inadequacy of lacrimal dr...

journal_title：Journal of glaucoma

authors： Henriques MJ,Vessani RM,Reis FA,de Almeida GV,Betinjane AJ,Susanna R Jr

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:To assess the reproducibility of retinal nerve fiber layer thickness and macular thickness measurements using OCT-3. METHODS:Randomly chosen eyes of healthy individuals were scanned following pupillary dilation by two trained operators (RGO, RV) using OCT-3 (software version A1.1, Carl Zeiss Meditec, Inc., Dub...

journal_title：Journal of glaucoma

authors： Gürses-Ozden R,Teng C,Vessani R,Zafar S,Liebmann JM,Ritch R

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:To determine the optimal OCT-3 scanning protocol. METHODS:Normal subjects, ocular hypertensive, and open-angle glaucoma patients were enrolled. The "fast" RNFL scan protocol consists of 3 consecutive circular scans, each containing 256 A-scans obtained in a single 1.92 second session. The "regular" RNFL scan p...

journal_title：Journal of glaucoma

authors： Zafar S,Gurses-Ozden R,Makornwattana M,Vessani R,Liebmann JM,Tello C,Ritch R

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:The GDx is a scanning laser polarimeter that assesses peripapillary nerve fiber layer thickness. In addition to the 14 existing outcome parameters, four new parameters have been described recently: the Ellipse Standard Deviation (ESD), the Normalized Superior Area (NSA), the Normalized Inferior Area (NIA) and t...

journal_title：Journal of glaucoma

authors： Colen TP,Tang NE,Mulder PG,Lemij HG

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:This study determined the rate of response to latanoprost compared with timolol in patients with glaucoma or ocular hypertension, whether some patients convert from non-responders to responders after more prolonged therapy, and whether this conversion represents a delayed response or random fluctuation. METHOD...

journal_title：Journal of glaucoma

authors： Camras CB,Hedman K,US Latanoprost Study Group.

更新日期：2003-12-01 00:00:00

abstract：PURPOSE:To evaluate three new approaches for staging severity of glaucomatous visual field defects using frequency doubling technology. PATIENTS AND METHODS:One hundred and four patients with either ocular hypertension or chronic glaucoma were tested with both standard automated perimetry (SAP, 30-2 Humphrey threshold...

journal_title：Journal of glaucoma

authors： Brusini P,Tosoni C

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To compare the replacement of every drug with latanoprost 0.005% once a day in glaucomatous eyes with poorly controlled intraocular pressure upon combination therapy, versus addition of latanoprost to the pre-existing treatment. PATIENTS AND METHODS: STUDY DESIGN:prospective, investigator-masked, two-center, ...

journal_title：Journal of glaucoma

authors： Gandolfi SA,Rossetti L,Cimino L,Mora P,Tardini M,Orzalesi N

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:To assess the prevalence of optic disc hemorrhage in Asian patients with established glaucoma using a recently described, highly sensitive detection method. MATERIALS AND METHODS:Patients entering a trial of glaucoma filtering surgery in Southeast Asia (The Singapore 5FU Study) were assessed for the presence o...

journal_title：Journal of glaucoma

authors： Gazzard G,Morgan W,Devereux J,Foster P,Oen F,Seah S,Khaw PT,Chew P

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:To characterize and compare the ocular comfort and symptoms of dorzolamide and tear-replacement drops (placebo) in healthy volunteers. PATIENTS AND METHODS:Subjects were randomized in a double-masked fashion to receive each medicine for 6 days twice daily. Patients used a visual analog scale to assess the qual...

journal_title：Journal of glaucoma

authors： Stewart WC,Stewart JA,Leech JN

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To compare the results of frequency-doubling technology perimetry (FDT), assumed to test the magnocellular visual pathway, and high-pass resolution perimetry (HRP), assumed to test the parvocellular visual pathway, in patients with ocular hypertension or glaucoma. PATIENTS AND METHODS:Forty-eight consecutive p...

journal_title：Journal of glaucoma

authors： Martin L,Wanger P,Vancea L,Göthlin B

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:To obtain retinal nerve fiber layer (RNFL) measurements by optical coherence tomography in a local, normal Hong Kong Chinese population and to identify the correlation of the measurement with age cross-sectionally. METHODS:A total of 129 normal Hong Kong Chinese volunteers of different age groups were recruite...

journal_title：Journal of glaucoma

authors： Mok KH,Lee VW,So KF

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:To describe a surgical technique to improve visualization and surgical access for trabeculectomy and implantation of aqueous drainage devices. MATERIALS AND METHODS:After the corneal traction suture (6-0 polygalactin; S-29 needle) is placed, a second suture is passed through Tenon's capsule alone, either at th...

journal_title：Journal of glaucoma

authors： Hill RA

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:To investigate the effects of dehydration and fasting on retrobulbar-vessel blood velocity in healthy subjects. METHODS:Twenty-eight eyes of 28 normal subjects without ocular disease were enrolled in this study. Each subject had a baseline color-Doppler imaging ultrasound of the central retinal artery, tempora...

journal_title：Journal of glaucoma

authors： Inan UU,Yücel A,Ermis SS,Oztürk F

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To evaluate the effect of a single treatment of contact diode laser transscleral cyclophotocoagulation (TSCP) on intraocular pressure (IOP) in patients with refractory glaucoma and perform a historical meta-analysis of the relationship between successful IOP control and various laser parameters. METHODS:Clinic...

journal_title：Journal of glaucoma

authors： Hauber FA,Scherer WJ

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To study the relationship between optic disc hemorrhages and four different groups of medications used in general vascular disease and diabetes. METHODS:The authors screened citizens of the city of Malmö, Sweden who were between 57 and 79 years old (32,918 subjects), in order to find individuals with undetecte...

journal_title：Journal of glaucoma

authors： Grødum K,Heijl A,Bengtsson B

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:To investigate the effects of topical instillation of 0.5% tranilast eye drops on intraocular pressure (IOP) and bleb formation after glaucoma filtering surgery. PATIENTS AND METHODS:This was a prospective, randomized, double-masked, and controlled clinical trial. A total of 52 eyes of 52 patients were randoml...

journal_title：Journal of glaucoma

authors： Chihara E,Dong J,Ochiai H,Hamada S

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:Axenfeld-Rieger syndrome is a genetically heterogeneous, autosomal dominant disorder that is characterized by anterior segment defects, glaucoma, and extraocular anomalies. This study examined the two genes known to cause Rieger syndrome, PITX2 and FOXC1, for mutations in five Brazilian families with Axenfeld-R...

journal_title：Journal of glaucoma

authors： Borges AS,Susanna R Jr,Carani JC,Betinjane AJ,Alward WL,Stone EM,Sheffield VC,Nishimura DY

更新日期：2002-02-01 00:00:00

abstract：PURPOSE:To compare the intraocular pressure-lowering effect of unoprostone isopropyl (unoprostone) 0.12% and latanoprost 0.005%. A correlation between the intraocular pressure-lowering effect of unoprostone and latanoprost was also evaluated. METHODS:A single-masked randomized study included 18 patients between 49 and...

journal_title：Journal of glaucoma

authors： Kobayashi H,Kobayashi K,Okinami S

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:To report the histopathologic and immunohistochemical findings from the iridectomy specimen of a patient with acquired unilateral iris heterochromia due to latanoprost. PATIENT AND METHODS:A 45-year-old woman with open-angle glaucoma and unilateral iris heterochromia was evaluated for uncontrolled intraocular ...

journal_title：Journal of glaucoma

authors： Tsai JC,Sivak-Callcott JA,Haik BG,Zhang J,McLean IW

更新日期：2001-10-01 00:00:00

abstract：:Many of these techniques have been adapted to investigate hemodynamic alterations, not only in glaucoma, but in diverse disorders such as diabetic retinopathy, macular degeneration, retinal dystrophies, and nonglaucomatous optic neuropathies. However, each of these techniques has limitations and there is not a single ...

journal_title：Journal of glaucoma

authors： Cioffi GA,Alm A

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:The mechanism by which the prostaglandin F2alpha-related antiglaucoma compound isopropyl unoprostone (referred to as unoprostone) reduces intraocular pressure is largely unknown. Another prostaglandin F2alpha-related compound, latanoprost, influences the activities of matrix metalloproteinases in ciliary muscle...

journal_title：Journal of glaucoma

authors： Kashiwagi K,Jin M,Suzuki M,Tanaka Y,Iizuka Y,Tsukahara S

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:To investigate the practice patterns among glaucoma subspecialists in the American Glaucoma Society regarding the management of blebitis. METHODS:An anonymous survey incorporating 14 questions regarding the management of blebitis was mailed to all current active American Glaucoma Society members, including pro...

journal_title：Journal of glaucoma

authors： Reynolds AC,Skuta GL,Monlux R,Johnson J

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:To estimate resource use and costs associated with the diagnosis and treatment of glaucoma and ocular hypertension in the Netherlands in 1996 and to determine how costs differed between patients, diagnoses, and hospitals. PATIENTS AND METHODS:Patient characteristics and glaucoma-related resource use were colle...

journal_title：Journal of glaucoma

authors： Oostenbrink JB,Rutten-van Mölken MP,Sluyter-Opdenoordt TS

更新日期：2001-06-01 00:00:00

abstract：PURPOSE:To evaluate the usefulness of the krypton laser for transscleral contact cyclophotocoagulation in the treatment of posttraumatic glaucoma. PATIENTS AND METHODS:A total of 18 eyes of 18 patients with therapy-resistant posttraumatic glaucoma treated with krypton laser cyclophotocoagulation from 1991 to 1996 were...

journal_title：Journal of glaucoma

authors： Raivio VE,Immonen IJ,Laatikainen LT,Puska PM

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:The pattern of the distribution of nerve fiber layer (NFL) thickness values across the retina may provide an early anatomic indication of glaucomatous disruption. We developed a method of analyzing polarimetry measurements that emphasizes the shape of the pattern of NFL thickness values. Sensitivity and specifi...

journal_title：Journal of glaucoma

authors： Essock EA,Sinai MJ,Fechtner RD,Srinivasan N,Bryant FD

更新日期：2000-12-01 00:00:00

abstract：PURPOSE:To report the efficacy and safety of inferior 180 degrees goniosynechialysis followed by diode laser peripheral iridoplasty in the treatment of chronic angle-closure glaucoma with total synechial angle closure. METHODS:Five patients with chronic angle-closure glaucoma and total synechial angle closure whose in...

journal_title：Journal of glaucoma

authors： Lai JS,Tham CC,Chua JK,Lam DS

更新日期：2000-10-01 00:00:00

abstract：PURPOSE:To correlate Humphrey visual field mean sensitivity and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry. METHODS:The authors studied 54 eyes of 34 patients who visited a university-based glaucoma clinic and had undergone scanning laser polarimetry and Humphrey perimetry with...

journal_title：Journal of glaucoma

authors： Kwon YH,Hong S,Honkanen RA,Alward WL

更新日期：2000-08-01 00:00:00

abstract：PURPOSE:To determine the clinical features and anatomic parameters in asymptomatic (creeping) and symptomatic, chronic, primary angle-closure glaucoma (PACG) as compared with open-angle glaucoma (OAG) and with control subjects with normal eyes. METHODS:Forty consecutive patients with each of the following four types o...

journal_title：Journal of glaucoma

authors： Sihota R,Gupta V,Agarwal HC,Pandey RM,Deepak KK

更新日期：2000-06-01 00:00:00

abstract：PURPOSE:To study the additive effect of latanoprost 0.005% in patients who have uncontrolled intraocular pressure (IOP) using timolol 0.5% and dorzolamide 2%. METHODS:Fifty-two consecutive patients with open-angle glaucoma who were using timolol and dorzolamide and were considered to have IOP above their defined targe...

journal_title：Journal of glaucoma

authors： Susanna R Jr,Nicolela MT,Oga E

更新日期：2000-04-01 00:00:00

abstract：PURPOSE:More than one million patients in the United States are treated for glaucoma, although little is known about the typical clinical characteristics of this group of patients and the type of therapy they receive. This study was conducted to describe the demographic and diagnostic characteristics of patients beginn...

journal_title：Journal of glaucoma

authors： Bohn RL,Gurwitz JH,Yeomans SM,Glynn RJ,Pasquale LR,Walker AM,Avorn J

更新日期：2000-02-01 00:00:00

abstract：PURPOSE:To evaluate an alternate method of covering the subconjunctival portion of the tube in aqueous shunt surgery. Evidence of tube erosion, graft-related infection, graft melting, or other associated intraocular complications were evaluated. METHODS:A retrospective study of 16 patients (17 eyes) who underwent tube...

journal_title：Journal of glaucoma

authors： Aslanides IM,Spaeth GL,Schmidt CM,Lanzl IM,Gandham SB

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:To measure the interobserver agreement of Heidelberg Retina Tomograph (HRT; Heidelberg Engineering, Heidelberg, Germany) parameters as a result of different observers' contour line placement. METHODS:The optic nerve heads of 50 patients with glaucoma were imaged with the HRT. Five observers traced each disc ma...

journal_title：Journal of glaucoma

authors： Hatch WV,Flanagan JG,Williams-Lyn DE,Buys YM,Farra T,Trope GE

更新日期：1999-08-01 00:00:00

abstract：PURPOSE:This randomized, masked, prospective study was conducted to compare the outcome of filtering surgery using doses of 0.2 mg/cc or 0.4 mg/cc of mitomycin C (MMC) in eyes that were at higher risk from previous conjunctival incisional surgery. METHODS:Eyes of 50 consecutive patients with primary open-angle, pseudo...

journal_title：Journal of glaucoma

authors： Sanders SP,Cantor LB,Dobler AA,Hoop JS

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:To discuss a case in which melanocytoma of the ciliary body presented with widespread pigment dispersion and elevated intraocular pressure (IOP). METHODS:A 64-year old woman presented with increased IOP and persistent anterior segment inflammation in her right eye. She had undergone a trabeculectomy for uncont...

journal_title：Journal of glaucoma

authors： Bhorade AM,Edward DP,Goldstein DA

更新日期：1999-04-01 00:00:00

abstract：PURPOSE:Impairment of the blood-aqueous barrier in unoperated eyes with pseudoexfoliation syndrome has been demonstrated by fluorescein angiography, fluorophotometry, measurement of aqueous flare, and determination of aqueous protein. We performed noninvasive quantification of aqueous flare using the laser flare-cell m...

journal_title：Journal of glaucoma

authors： Nguyen NX,Küchle M,Martus P,Naumann GO

更新日期：1999-02-01 00:00:00

abstract：PURPOSE:To compare the effect of unoprostone isopropyl 0.12% to that of timolol maleate 0.5% solution given twice daily on the diurnal curve of intraocular pressure (IOP) in patients with primary open-angle glaucoma or ocular hypertension. METHODS:In this investigator-masked, single-center, parallel-group comparison, ...

journal_title：Journal of glaucoma

authors： Stewart WC,Stewart JA,Kapik BM

更新日期：1998-12-01 00:00:00